If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. You may also experience withdrawal symptoms.Methadone should be given with caution and the initial dose reduced rein certain patients, such as the elderly and debilitated and those with severe impairment of hepatic or renal f
HIV drugs, such as ritonavir or indinavir. Taking these drugs with methadone may cause increased drowsiness and slowed breathing. Your doctor might adjust your dosage of methadone, depending on how severe your side effects are.Published animal data have reported increased neonatal mortality in the offspring of male rodents that were treated with me
Physical dependence is manifested by withdrawal symptoms after abrupt discontinuation of a drug or upon administration of an antagonist. Physical dependence and/or tolerance are not unusual during chronic opioid therapy.Addiction and misuse warning: Methadone comes with a risk of addiction even when it’s used the right way. This can lead to drug
Methadone hydrochloride tablets can cause life-threatening heartbeat problems that can lead to death. Most heartbeat problems have happened hinein people using large doses of methadone hydrochloride tablets for pain treatment.The initial methadone dose should be carefully titrated to the individual. Too rapid titration for the patient's sensitivity
If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. You may also experience withdrawal symptoms.The dose conversion scheme below is derived from various consensus guidelines for converting chronic pain patients to methadone from morphine. Clinicians should consult published co